NADPH oxidase 5 activation; a novel approach to human sperm cryoinjury

Human Neutrophil Cytosolic Activation Factor of the NADPH Oxidase

The kinetics of sodium dodecyl sulfate-induced activation of respiratory burst oxidase (NADPH oxidase) in a fully soluble cell-free system from resting (control) or phorbol myristate acetate (PMA)-stimulated human neutrophils were investigated. In a cell-free system containing solubilized membranes and cytosol fractions (cytosol) derived from control neutrophils (control cell-free system), the ...

NADPH Oxidase Deficiency: A Multisystem Approach

The immune system is a complex system able to recognize a wide variety of host agents, through different biological processes. For example, controlled changes in the redox state are able to start different pathways in immune cells and are involved in the killing of microbes. The generation and release of ROS in the form of an "oxidative burst" represent the pivotal mechanism by which phagocytic...

Involvement of Activation of Nadph Oxidase

ABSTRACT Zinc is employed as a supplement; however, zinc-related nephropathy is not generally known. In this study, we investigatecl zinc-induced renal cell iajury using a pig kidney-derived cultured renal epithelial cell line, LLC-PKI, with proximal kidney tubule-like features, and examined the involvement of free radicals and extracellular signal-regu]ated kinase (ERK) in the cell injury. The...

During Phagocytosis NADPH Oxidase Activation and Assembly

P-21 activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils Pak regulates phagocyte NADPH oxidase

P-21 activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils Pak regulates phagocyte NADPH oxidase Kendra D. Martyn, Moon-Ju Kim, Mark T. Quinn, Mary C. Dinauer and Ulla G. Knaus These authors contributed equally to this work Dr. Martyn and Dr. Kim performed research Dr. Quinn and Dr. Dinauer contributions are essential reagents and manuscript revision Dr. Knaus designed ...